XL184 free base (Cabozantinib)

Catalog No.: A10996

VEGFR inhibitor

XL184 free base (Cabozantinib)

XL184 free base (Cabozantinib) Chemical Structure

CAS NO. 849217-68-1

XL184 free base (Cabozantinib) is a small molecule designed to inhibit multiple receptor tyrosine kinases, specifically MET and VEGFR2.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $60.00

Special Price $48.00

10 mg

Regular Price: $75.00

Special Price $60.00

50 mg

Regular Price: $98.00

Special Price $78.40

100 mg

Regular Price: $145.00

Special Price $116.00

10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

XL184 free base (Cabozantinib) is a small molecule designed to inhibit multiple receptor tyrosine kinases, specifically MET and VEGFR2.
In vitro (25°C) DMSO 100 mg/mL (199.39 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10996
Actions Inhibitor
M. Wt 501.5
Formula C28H24FN3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 849217-68-1
Synonyms BMS-907351
SMILES COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

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