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XMT-1519 conjugate-1

Catalog No.: A41380
Drug-Linker Conjugate for ADC
XMT-1519 conjugate-1 is a drug-linker conjugate designed for use in antibody-drug conjugate (ADC) applications. This compound facilitates the conjugation with the HER-2 monoclonal antibody Calotatug (XMT-1519), enabling the targeted delivery of therapeutic agents to cancer cells that express the HER-2 receptor. It is an essential component for the synthesis of ADCs aimed at enhancing anticancer efficacy while minimizing off-target effects.
XMT-1519 conjugate-1 2720500-19-4 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$630.00
In stock
5mg
$1,615.00
In stock
10mg
$2,730.00
In stock
25mg
$5,735.00
In stock
50mg
$9,240.00
In stock
100mg
$14,880.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXMT-1519 conjugate-1 is a drug-linker conjugate designed for use in antibody-drug conjugate (ADC) applications. This compound facilitates the conjugation with the HER-2 monoclonal antibody Calotatug (XMT-1519), enabling the targeted delivery of therapeutic agents to cancer cells that express the HER-2 receptor. It is an essential component for the synthesis of ADCs aimed at enhancing anticancer efficacy while minimizing off-target effects.
Product Information
Catalog NumA41380
FormulaC101H149N23O42
Molecular Weight2357.39
CAS Number2720500-19-4
SMILESO=C(C1=C(N=C(O1)C)CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCOC([C@H](C)NC(CCOCCOCCNC(CC[C@@H](C(NCC(NCC(NCC(NCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=O)=O)=O)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C7=C(N=C(O7)C)CC)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC