YL93

Name: YL93
Brand: Adooq Bioscience
SKU: A53861
Rating: 5 (288 reviews)

Catalog No.: A53861

MDM2/4 Dual Inhibitor

YL93 is a MDM2/4 dual inhibitor, exhibiting Ki values of 0.64 μM for MDM4 and 1.1 nM for MDM2. This compound effectively induces cell-cycle arrest and promotes apoptosis in p53-dependent contexts. YL93 is valuable for research applications focused on cancer biology and the modulation of p53 signaling pathways.

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Biological Activity

Description	YL93 is a MDM2/4 dual inhibitor, exhibiting Ki values of 0.64 μM for MDM4 and 1.1 nM for MDM2. This compound effectively induces cell-cycle arrest and promotes apoptosis in p53-dependent contexts. YL93 is valuable for research applications focused on cancer biology and the modulation of p53 signaling pathways.

Product Information

Catalog Num	A53861
Formula	C37H38Cl2F2N4O4
Molecular Weight	711.62
CAS Number	2771313-42-7
SMILES	FC(C(Cl)=CC=C1)=C1[C@@H]([C@@H](N[C@H]2CC(C)(C)C)C(NC3=CC=C(C=C3OC)C(O)=O)=O)[C@]2(C4=CC=C(Cl)C=C4F)CNCC5=CC=NC=C5

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