Zevontabart (MYTX-011 Antibody) is a pH-dependent antibody-drug conjugate (ADC) targeting c-MET. It interferes with the trafficking of c-MET, leading to reduced receptor recycling and enhanced endocytosis in c-MET-expressing cells. Zevontabart demonstrates significant cytotoxicity against solid tumor cells and exhibits anti-tumor efficacy in non-small cell lung cancer xenograft models. This reagent is valuable for research in non-small cell lung cancer and related studies.
Zevontabart (MYTX-011 Antibody) is a pH-dependent antibody-drug conjugate (ADC) targeting c-MET. It interferes with the trafficking of c-MET, leading to reduced receptor recycling and enhanced endocytosis in c-MET-expressing cells. Zevontabart demonstrates significant cytotoxicity against solid tumor cells and exhibits anti-tumor efficacy in non-small cell lung cancer xenograft models. This reagent is valuable for research in non-small cell lung cancer and related studies.
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