ZG-2033

Catalog No.: A75629
HIF-2α Agonist
ZG-2033 is a potent orally active HIF-2α agonist, exhibiting an EC50 value of 490 nM in luciferase reporter gene assays. This compound has been shown to alleviate anemia and operates synergistically with AKB-6548 in enhancing erythropoiesis. ZG-2033 serves as a valuable tool for research focused on renal anemia and related therapeutic interventions.
Grouped product items
Size Price Stock Qty
1mg
$340.00
In stock
5mg
$1,050.00
In stock
10mg
$1,720.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZG-2033 is a potent orally active HIF-2α agonist, exhibiting an EC50 value of 490 nM in luciferase reporter gene assays. This compound has been shown to alleviate anemia and operates synergistically with AKB-6548 in enhancing erythropoiesis. ZG-2033 serves as a valuable tool for research focused on renal anemia and related therapeutic interventions.
Product Information
Catalog NumA75629
FormulaC15H14N2O2S
Molecular Weight286.35
CAS Number2685739-28-8
SMILESCOC1=CC(OC)=CC(NC2=NSC3=CC=CC=C23)=C1
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