1-Azakenpaullone

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Catalog No. A14303

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
1-Azakenpaullone 2mg A14303-2

Regular Price: $120.00

Special Price: $102.00

1-Azakenpaullone 5mg A14303-5

Regular Price: $237.00

Special Price: $201.45

1-Azakenpaullone 10mg A14303-10

Regular Price: $450.00

Special Price: $382.50

1-Azakenpaullone 10mM * 1mL in DMSO A14303-10mM-D

Regular Price: $256.00

Special Price: $217.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.

1-Azakenpaullone

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Chemical Information

Catalog Num A14303
Actions No
M. Wt 328.16
Formula C15H10BrN3O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 676596-65-9
Synonyms N/A
SMILES code C1C2=C(C3=C(C=CC=N3)NC1=O)NC4=C2C=C(C=C4)Br
Chemical Name Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-bromo-7,12-dihydro-

Biological Activity

Description
1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
Targets
GSK-3α GSK-3β

Solubility

Solubility (25°C)* In vitro DMSO 66 mg/mL (201.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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