ABT-751 (E-7010)

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Microtubule Associated inhibitor

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Catalog No. A10024

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ABT-751 10mg A10024-10

Regular Price: $80.00

Special Price: $64.00

ABT-751 50mg A10024-50

Regular Price: $330.00

Special Price: $264.00

ABT-751 100mg A10024-100

Regular Price: $450.00

Special Price: $360.00

ABT-751 200mg A10024-200

Regular Price: $700.00

Special Price: $560.00

ABT-751 10mM * 1mL in DMSO A10024-10mM-D

Regular Price: $92.00

Special Price: $73.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.

ABT-751 (E-7010)

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Chemical Information

Catalog Num A10024
Actions Inhibitor
M. Wt 371.4
Formula C18H17N3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 141430-65-1
Synonyms ABT751
SMILES code COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O
Chemical Name N-[2-[(4-Hydroxyphenyl)amino]-3-pyr idinyl]-4-methoxybenzenesulfonamide

Biological Activity

Description
ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.
Targets
Microtubules

Solubility

Solubility (25°C) * In vitro DMSO 74 mg/mL (199.24 mM)
Water <1 mg/mL (<1 mM)
Ethanol 12 mg/mL (32.3 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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