Acetyl-Calpastatin (184-210) (human)

Selective calpain inhibitor

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Catalog No. A15290

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Acetyl-Calpastatin (184-210) (human) 1mg A15290-1
$235.00
Acetyl-Calpastatin (184-210) (human) 5mg A15290-5
$635.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid ??-protein (A??) 42, A??40 and A??42 ratio.

Acetyl-Calpastatin (184-210) (human)

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Chemical Information

Catalog Num A15290
Actions Inhibitor
M. Wt 3177.65
Formula C142H230N36O44S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 123714-50-1
Synonyms N/A
SMILES code CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NC(CCCCN)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)
Chemical Name N/A

Biological Activity

Description
Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid ??-protein (A??) 42, A??40 and A??42 ratio.

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