Cysteine protease

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  1. Cathepsin K Inhibitor

    Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.
  2. Cathepsin Inhibitor

    Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
  3. Cathepsin K inhibitor

    Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys.
  4. Cathepsin K inhibitor

    L-873724 is a potent, orally bioavailable, selective and reversible non-basic cathepsin K inhibitor.
  5. Cathepsin B inhibitor

    CA-074 is a potent inhibitor of cathepsin B with a Ki of 2 to 5 nM.
  6. Cysteine Protease inhibitor

    E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.
  7. Cysteine Protease inhibitor

    Loxistatin Acid, a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
  8. Cysteine Protease inhibitor

    E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
  9. cathepsin S inhibitor

    Petesicatib is a cathepsin S inhibitor, used in research of immune diseases.
  10. Cathepsin S inhibitor

    Z-FL-COCHO is a novel Cathepsin S inhibitor.
  11. Cathepsin B inhibitor

    CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro.
  12. cathepsin C substrate

    Gly-Phe-beta-naphthylamide is a cathepsin C substrate. The compound is described to accumulate inside lysosomes leading to their destruction.
  13. reversible Calpain inhibitor

    SJA6017 is a cell permeable peptide aldehyde which functions as a reversible calpain inhibitor.
  14. Cysteine Protease inhibitor

    Leupeptin hemisulfate is a reversible inhibitor of trypsin-like and cysteine proteases such as calpain.
  15. Cysteine Protease inhibitor

    MG-101 (ALLN) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
  16. Calpain inhibitor

    PD 151746 is a selective, cell-permeable calpain inhibitor with Ki of 0.26 uM for μ-Calpain, about 20-fold selectivity over m-calpain.
  17. Irreversible Cysteine Protease inhibitor

    Z-FA-FMK is an irreversible cysteine protease inhibitor.
  18. Calpain Inhibitor

    Calpain Inhibitor II, ALLM is a cell-permeable inhibitor of calpain I, calpain II, cathepsin L and cathepsin B with Ki values of 120 nM, 230 nM, 0.6 nM and 100 nM, respectively.
  19. Selective calpain inhibitor

    Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
  20. Calpain inhibitor

    Calpeptin is a cell permeable calpain inhibitor.
  21. Cathepsin K Inhibitor

    L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S.
  22. Calpain Inhibitor III

    MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent cysteine protease which has been implicated in apoptosis of immune cells as well as neuronal cells.
  23. Non-peptide calpain inhibitor

    PD 150606 is a cell-permeable, non-competitive, selective, non-peptide Ca2+ dependent calpain inhibitor for calpain-1 and for calpain-2 directed towards the Ca2+ binding sites of calpain.
  24. Human cathepsin L inhibitor

    SID 26681509 is a reversible and potent human cathepsin L inhibitor. SID 26681509 displays no inhibitory activity of cathepsin G.
  25. Cathepsin S inhibitor

    LY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases.
  26. Cysteine protease inhibitor

    Z-FA-FMK is an irreversible inhibitor of cysteine protease
  27. Calpain inhibitor

    SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly.
  28. Cysteine protease inhibitor

    LHVS is a potent, non-selective cysteine protease inhibitor. LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion.
  29. Cathepsin S inhibitor

    MIV-247 is a selective cathepsin S inhibitor with Kis of 2.1, 4.2 and 7.5 nM for human, mouse and cynomolgus monkey cathepsin S, respectively.
  30. cysteine protease inhibitor

    Cysteine Protease inhibitor is an inhibitor of cysteine protease.
  31. cathepsin inhibitor

    VBY-825 is a novel, reversible cathepsin inhibitor with high potency against cathepsins B, L, S and V.
  32. cathepsin K inhibitor

    MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.
  33. human cathepsin L inhibitor

    Oxocarbazate, also known as CID23631927, is an inhibitor of human cathepsin L.
  34. Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity.

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