AKT inhibitor VIII (AKTI-1/2)

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AKT inhibitor

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Catalog No. A11286

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AKT inhibitor VIII 5mg A11286-5

Regular Price: $90.00

Special Price: $76.50

AKT inhibitor VIII 10mg A11286-10

Regular Price: $140.00

Special Price: $119.00

AKT inhibitor VIII 25mg A11286-25

Regular Price: $300.00

Special Price: $255.00

AKT inhibitor VIII 50mg A11286-50

Regular Price: $550.00

Special Price: $467.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 = 58 nM, 210 nM, and 2.12 ?M for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays).

AKT inhibitor VIII (AKTI-1/2)

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Chemical Information

Catalog Num A11286
Actions Inhibitor
M. Wt 551.6
Formula C34H29N7O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 612847-09-3
Synonyms No
SMILES code C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC7=C(C=C6N=C5C8=CC=CC=C8)N=CN7
Chemical Name 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one

Biological Activity

Description
AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 = 58 nM, 210 nM, and 2.12 ?M for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays).
Targets
Akt1 Akt2 Akt3
58 nM210 nM2119 nM

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