AMG 548

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p38 MAPK inhibitor

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Catalog No. A10970

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AMG 548 5mg A10970-5
$150.00
AMG 548 10mg A10970-10
$250.00
AMG 548 50mg A10970-50
$800.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα.

AMG 548

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Chemical Information

Catalog Num A10970
Actions Inhibitor
M. Wt 461.56
Formula C29H27N5O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 864249-60-5
Synonyms AMG-548, AMG548
SMILES code N/A
Chemical Name (S)-2-((2-amino-3-phenylpropyl)amino)-3-methyl-5-(naphthalen-2-yl)-6-(pyridin-4-yl)pyrimidin-4(3H)-one

Biological Activity

Description
AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα.

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