AMG517
AMG 517 is a potent and selective TRPV1 antagonist.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's AMG517 has been cited by 2 publications
- Jun Hai, .et al. , Biosci Biotechnol Biochem, 2020, Jul 7;1-7 PMID: 32633621
- Hai J, .et al. , Biomed Res, 2018, 39(6):279-286 PMID: 30531157
Biological Activity
| Description | AMG 517 is a potent and selective TRPV1 antagonist. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A12727 |
|---|---|
| Formula | C20H13F3N4O2S |
| Molecular Weight | 430.4 |
| CAS Number | 659730-32-2 |
| SMILES | CC(=O)NC1=NC2=C(C=CC=C2S1)OC3=NC=NC(=C3)C4=CC=C(C=C4)C(F)(F)F |
| Synonyms | AMG 517, AMG-517 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 84 mg/mL (195.16 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 10% Tween 80 | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.23 mL | 116.17 mL | 232.34 mL |
| 0.5 mM | 4.65 mL | 23.23 mL | 46.47 mL |
| 1 mM | 2.32 mL | 11.62 mL | 23.23 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.65 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
