Amlodipine

Catalog No.: A10068
L-type calcium channel blocker
Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
Grouped product items
Product Name Price Stock Qty
Amlodipine 500mg
$45.00
In stock
Amlodipine 10mM * 1mL in DMSO
$61.00
In stock
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Biological Activity
Discription Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
Targets
Target Value
Product Information
Catalog Num A10068
Formula C20H25ClN2O5
Molecular Weight 408.9
CAS Number 88150-42-9
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Synonyms Istin, Norvasc, Caduet
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 71 mg/mL (173.64 mM)
Water Insoluble
Ethanol 71 mg/mL (173.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.46 mL 122.28 mL 244.56 mL
0.5 mM 4.89 mL 24.46 mL 48.91 mL
1 mM 2.45 mL 12.23 mL 24.46 mL
5 mM 0.49 mL 2.45 mL 4.89 mL
Useful Calculator

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