Amlodipine

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L-type calcium channel blocker

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Catalog No. A10068

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Amlodipine 100mg A10068-100

Regular Price: $40.00

Special Price: $34.00

Amlodipine 500mg A10068-500

Regular Price: $150.00

Special Price: $127.50

Amlodipine 10mM * 1mL in DMSO A10068-10mM-D

Regular Price: $61.00

Special Price: $51.85

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.

Amlodipine

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Chemical Information

Catalog Num A10068
Actions Blocker
M. Wt 408.9
Formula C20H25ClN2O5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 88150-42-9
Synonyms Istin, Norvasc, Caduet
SMILES code CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Chemical Name (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Biological Activity

Description
Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.

Solubility

Solubility (25°C)* In vitro DMSO 82 mg/mL (200.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol 82 mg/mL (200.54 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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