Apilimod

Catalog No.: A13794
IL-12/IL-23 inhibitor
Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM.
Grouped product items
Product Name Price Stock Qty
Apilimod 5mg
$45.00
In stock
Apilimod 10mg
$77.00
In stock
Apilimod 25mg
$135.00
In stock
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Biological Activity
Discription Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM.
Targets
Target Value
Product Information
Catalog Num A13794
Formula C23H26N6O2
Molecular Weight 418.498
CAS Number 541550-19-0
SMILES CC1=CC=CC(=C1)/C=N/NC2=NC(=NC(=C2)N3CCOCC3)OCCC4=CC=CC=N4
Synonyms Sta 5326, Sta5326, Sta-5326
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 74 mg/mL (176.82 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.89 mL 119.47 mL 238.95 mL
0.5 mM 4.78 mL 23.89 mL 47.79 mL
1 mM 2.39 mL 11.95 mL 23.89 mL
5 mM 0.48 mL 2.39 mL 4.78 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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