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|Storage||at -20°C 2 years|
|ARN-509 is an androgen receptor antagonist with potential antineoplastic activity. ARN-509 binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR-responsive genes.|
|Solubility (25°C) *||In vitro||DMSO||18 mg/mL (37.7 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||5 mg/mL (10.47 mM)|
|In vivo||0.5% CMC, pH4.0||14 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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