AS-605240

Name: AS-605240
Brand: Adooq Bioscience
SKU: A10088
Rating: 5 (288 reviews)

Catalog No.: A10088

PI3K Inhibitor

AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.

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Grouped product items
Size	Price	Stock
5mg	$25.00	In stock
10mg	$35.00	In stock
25mg	$75.00	In stock
50mg	$140.00	In stock
100mg	$240.00	In stock
200mg	$360.00	In stock
500mg	$590.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description

AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A10088
Formula	C12H7N3O2S
Molecular Weight	257.3
CAS Number	648450-29-7
SMILES	C1=CC2=NC=CN=C2C=C1/C=C\3/C(=O)NC(=O)S3
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	0.38 mg/mL (1.47 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.87 mL	194.33 mL	388.65 mL
0.5 mM	7.77 mL	38.87 mL	77.73 mL
1 mM	3.89 mL	19.43 mL	38.87 mL
5 mM	0.78 mL	3.89 mL	7.77 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂