AS-605240

Catalog No.: A10088
PI3K Inhibitor
AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.
Grouped product items
Product Name Price Stock Qty
AS-605240 10mg
$40.00
In stock
AS-605240 25mg
$100.00
In stock
AS-605240 50mg
$180.00
In stock
AS-605240 100mg
$260.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.
Targets
Target Value
Product Information
Catalog Num A10088
Formula C12H7N3O2S
Molecular Weight 257.3
CAS Number 648450-29-7
SMILES C1=CC2=NC=CN=C2C=C1/C=C\3/C(=O)NC(=O)S3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 0.38 mg/mL (1.47 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC+0.25% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.87 mL 194.33 mL 388.65 mL
0.5 mM 7.77 mL 38.87 mL 77.73 mL
1 mM 3.89 mL 19.43 mL 38.87 mL
5 mM 0.78 mL 3.89 mL 7.77 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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