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AS703026 (Pimasertib)

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Catalog No. A10089
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Availability: In stock

Product Name Catalog No. Price Qty
AS703026 5mg A10089-5

Regular Price: $40.00

Special Price: $32.00

AS703026 10mg A10089-10

Regular Price: $70.00

Special Price: $56.00

AS703026 50mg A10089-50

Regular Price: $180.00

Special Price: $144.00

AS703026 100mg A10089-100

Regular Price: $300.00

Special Price: $240.00

AS703026 10mM * 1mL in DMSO A10089-10mM-D

Regular Price: $93.00

Special Price: $74.40

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation.

AS703026 (Pimasertib)

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Publications citing Adooq Products

Chemical Information

Catalog Num A10089
Actions Inhibitor
M. Wt 431.2
Formula C15H15FIN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1236699-92-5
Synonyms AS-703026, MSC1936369B
SMILES code C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O
Chemical Name N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide

Biological Activity

Description AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation.

Solubility

Solubility (25°C) * In vitro DMSO 86 mg/mL (199.44 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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