AZD1080

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GSK3 inhibitor

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Catalog No. A12819

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD1080 5mg A12819-5

Regular Price: $160.00

Special Price: $136.00

AZD1080 10mg A12819-10

Regular Price: $290.00

Special Price: $246.50

AZD1080 25mg A12819-25

Regular Price: $520.00

Special Price: $442.00

AZD1080 50mg A12819-50

Regular Price: $780.00

Special Price: $663.00

AZD1080 10mM * 1mL in DMSO A12819-10mM-D

Regular Price: $206.00

Special Price: $175.10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

AZD1080

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Chemical Information

Catalog Num A12819
Actions Inhibitor
M. Wt N/A
Formula N/A
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 612487-72-6
Synonyms AZD 1080, AZD-1080
SMILES code C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2
Chemical Name N/A

Biological Activity

Description
AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Targets
GSK-3α GSK-3β
6.9 nM31 nM

Solubility

Solubility (25°C) * In vitro DMSO 52 mg/mL (155.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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