AZD1152

Aurora Kinase inhibitor

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Catalog No. A15011

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD1152 20mg A15011-20
$300.00
AZD1152 50mg A15011-50
$470.00
AZD1152 100mg A15011-100
$920.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD1152 is a pro-drug that rapidly undergoes phosphatase-mediated cleavage in serum to release barasertib-hQPA, a selective Aurora B kinase inhibitor that has shown preliminary activity in clinical studies of patients with acute myeloid leukemia (AML).

AZD1152

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Chemical Information

Catalog Num A15011
Actions Inhibitor
M. Wt 587.54
Formula C26H31FN7O6P
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 722543-31-9
Synonyms Barasertib, AZD-1152, AZD 1152
SMILES code CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O
Chemical Name 2-[ethyl-[3-[4-[[5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl]amino]quinazolin-7-yl]oxypropyl]amino]ethyl dihydrogen phosphate

Biological Activity

Description
AZD1152 is a pro-drug that rapidly undergoes phosphatase-mediated cleavage in serum to release barasertib-hQPA, a selective Aurora B kinase inhibitor that has shown preliminary activity in clinical studies of patients with acute myeloid leukemia (AML).

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