AZD2858

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GSK-3β inhibitor

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Catalog No. A13060

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD2858 10mg A13060-10

Regular Price: $80.00

Special Price: $68.00

AZD2858 25mg A13060-25

Regular Price: $160.00

Special Price: $136.00

AZD2858 50mg A13060-50

Regular Price: $280.00

Special Price: $238.00

AZD2858 100mg A13060-100

Regular Price: $500.00

Special Price: $425.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.

AZD2858

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Chemical Information

Catalog Num A13060
Actions Inhibitor
M. Wt 453.52
Formula C21H23N7O3S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 486424-20-8
Synonyms AZD-2858, AZD 2858
SMILES code CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N
Chemical Name Pyrazinecarboxamide,3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-

Biological Activity

Description
AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.
Targets
GSK-3
68 nM

Solubility

Solubility (25°C) * In vitro DMSO 7 mg/mL (15.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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