AZD2858

Catalog No.: A13060
GSK-3β inhibitor
AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.
Grouped product items
Product Name Price Stock Qty
AZD2858 10mg
$80.00
In stock
AZD2858 25mg
$160.00
In stock
AZD2858 50mg
$280.00
In stock
AZD2858 100mg
$500.00
In stock
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Biological Activity
Discription AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.
Targets
Target Value
Product Information
Catalog Num A13060
Formula C21H23N7O3S
Molecular Weight 453.52
CAS Number 486424-20-8
SMILES CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N
Synonyms AZD-2858, AZD 2858
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 6 mg/mL (13.23 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.25 mL 220.5 mL
0.5 mM 4.41 mL 22.05 mL 44.1 mL
1 mM 2.2 mL 11.02 mL 22.05 mL
5 mM 0.44 mL 2.2 mL 4.41 mL
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This equation is commonly abbreviated as: C1V1 = C2V2

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