Baricitinib phosphate

Name: Baricitinib phosphate
Brand: Adooq Bioscience
SKU: A15014
Rating: 5 (288 reviews)

Catalog No.: A15014

JAK inhibitor

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

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Baricitinib phosphate 1187595-84-1 JAK inhibitor

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Grouped product items
Size	Price	Stock
5mg	$35.00	In stock
10mg	$50.00	In stock
25mg	$85.00	In stock
50mg	$110.00	In stock
100mg	$140.00	In stock
500mg	$360.00	In stock
*10mM 1mL in DMSO**	$45.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

Targets

Target	Value

Product Information

Catalog Num	A15014
Formula	C16H20N7O6PS
Molecular Weight	469.41
CAS Number	1187595-84-1
SMILES	CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
Synonyms	INCB 028050, LY 3009104, INCB028050, LY3009104, LY-3009104, INCB-028050
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	85 mg/mL (181.08 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.3 mL	106.52 mL	213.03 mL
0.5 mM	4.26 mL	21.3 mL	42.61 mL
1 mM	2.13 mL	10.65 mL	21.3 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂