BAY 11-7085

κB/IKK inhibitor

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Catalog No. A12470

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BAY 11-7085 10mg A12470-10

Regular Price: $70.00

Special Price: $56.00

BAY 11-7085 25mg A12470-25

Regular Price: $150.00

Special Price: $120.00

BAY 11-7085 50mg A12470-50

Regular Price: $240.00

Special Price: $192.00

BAY 11-7085 10mM * 1mL in DMSO A12470-10mM-D

Regular Price: $55.00

Special Price: $44.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM

BAY 11-7085

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Chemical Information

Catalog Num A12470
Actions Inhibitor
M. Wt 249.33
Formula C13H15NO2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 196309-76-9
Synonyms Bay 11-7083, BAY11-7085
SMILES code CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N
Chemical Name (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile

Biological Activity

Description
BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM
Targets
IκBα?phosphorylation
10 μM

Solubility

Solubility (25°C)* In vitro DMSO 50 mg/mL (200.53 mM)
Water <1 mg/mL (<1 mM)
Ethanol 50 mg/mL (200.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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