BI-78D3

JNK inhibitor

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Catalog No. A13683

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BI-78D3 10mg A13683-10
$120.00
BI-78D3 25mg A13683-25
$250.00
BI-78D3 50mg A13683-50
$400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38?? and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).

BI-78D3

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Chemical Information

Catalog Num A13683
Actions Inhibitor
M. Wt 379
Formula C13H9N5O5S2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 883065-90-5
Synonyms BI 78D3, BI78D3
SMILES code C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
Chemical Name 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one,BI 78D3

Biological Activity

Description
BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38?? and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).
Targets
JNK
280 nM

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