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BKM120 (NVP-BKM120, Buparlisib)


PI3K Inhibitor‎

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Catalog No. A11016

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BKM120 5mg A11016-5

Regular Price: $60.00

Special Price: $54.00

BKM120 10mg A11016-10

Regular Price: $90.00

Special Price: $81.00

BKM120 25mg A11016-25

Regular Price: $100.00

Special Price: $90.00

BKM120 50mg A11016-50

Regular Price: $120.00

Special Price: $108.00

BKM120 (NVP-BKM120) 10mM * 1mL in DMSO A11016-10mM-D

Regular Price: $60.00

Special Price: $54.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BKM120 (NVP-BKM120) is a bioavailable specific oral pan-class I phosphatidylinositol 3-kinase (PI3K) kinase inhibitor.

BKM120 (NVP-BKM120, Buparlisib)

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Chemical Information

Catalog Num A11016
Actions Inhibitor
M. Wt 410.4
Formula C18H21F3N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 944396-07-0
Synonyms N/A
Chemical Name 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine

Biological Activity

BKM120 (NVP-BKM120) is a bioavailable specific oral pan-class I phosphatidylinositol 3-kinase (PI3K) kinase inhibitor.
Target Value
p110αIC50: 52nM
p110δIC50: 116nM
p110βIC50: 166nM
p110γIC50: 262nM
Vps34IC50: 2.4μM
mTORIC50: 4.6μM
DNA-PKIC50: >5μM
PI4KβIC50: >25μM


Solubility (25°C) * In vitro DMSO 82 mg/mL (199.8 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.87 mM)
In vivo 0.5% CMC Na 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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