Diphenyleneiodonium chloride has been shown to be a potent irreversible inhibitor of NOS2 (iNOS) from macrophages and NOS3 (eNOS) from endothelial cells.
Diphenyleneiodonium chloride has been shown to be a potent irreversible inhibitor of NOS2 (iNOS) from macrophages and NOS3 (eNOS) from endothelial cells.
Product Information
Catalog Num
A13359
Formula
C12H8l.Cl
Molecular Weight
314.55
CAS Number
4673-26-1
SMILES
C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]
Synonyms
Dibenziodolium chloride; DPI Chloride
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
12 mg/mL (38.14 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
3% DMSO+40% PEG 300+2% Tween 80+ddH2O
0.4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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