Erlotinib HCl ON SALE EGFR inhibitor

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Catalog No. A10362

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Erlotinib Hydrochloride 100mg A10362-100

Regular Price: $40.00

Special Price: $34.00

Erlotinib Hydrochloride 250mg A10362-250

Regular Price: $80.00

Special Price: $68.00

Erlotinib Hydrochloride 500mg A10362-500

Regular Price: $120.00

Special Price: $102.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

Erlotinib HCl

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Chemical Information

Catalog Num A10362
Actions Inhibitor
M. Wt 429.9
Formula C22H23N3O4.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 183319-69-9
Synonyms CP-358774, OSI-774, NSC 718781
SMILES code COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Chemical Name N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride

Biological Activity

Description
Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
Targets
HER1/EGFR (Cell-free assay)
2 nM

Solubility

Solubility (25°C) * In vitro DMSO 3 mg/mL (6.97 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO, 0.5% CMC Na and 15% Captisol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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A10043 AEE788 <1 mg/mL 88 mg/mL <1 mg/mL
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A10612 Mubritinib (TAK 165) 13 mg/mL <1 mg/mL <1 mg/mL
A10638 Neratinib (HKI-272) 2 mg/mL <1 mg/mL <1 mg/mL
A10678 OSI-420 83 mg/mL 2 mg/mL <1 mg/mL
A10702 PD153035 (HCl salt) <1 mg/mL <1 mg/mL <1 mg/mL
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A11236 TAK-285 <1 mg/mL 110 mg/mL 54 mg/mL
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A10990 WZ3146 <1 mg/mL 93 mg/mL <1 mg/mL
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