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Flavopiridol HCl


CDK inhibitor

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Catalog No. A11045

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Flavopiridol HCl 10mg A11045-10

Regular Price: $60.00

Special Price: $48.00

Flavopiridol HCl 25mg A11045-25

Regular Price: $120.00

Special Price: $96.00

Flavopiridol HCl 50mg A11045-50

Regular Price: $200.00

Special Price: $160.00

Flavopiridol HCl 100mg A11045-100

Regular Price: $350.00

Special Price: $280.00

Flavopiridol HCl 10mM * 1mL in DMSO A11045-10mM-D

Regular Price: $85.00

Special Price: $68.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Flavopiridol HCl is an inhibitor of cyclin-dependent kinases. The (-)-cis form induces apoptosis in particular tumor cells.

Flavopiridol HCl

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Chemical Information

Catalog Num A11045
Actions Inhibitor
M. Wt 438.3
Formula C21H20ClNO5.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 131740-09-5
Synonyms N/A
SMILES code CN1CC[[email protected]@H]([[email protected]@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
Chemical Name (-)-2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride

Biological Activity

Flavopiridol HCl is an inhibitor of cyclin-dependent kinases. The (-)-cis form induces apoptosis in particular tumor cells.
CDK1 (Cell-free assay) CDK2 (Cell-free assay) CDK4 (Cell-free assay) CDK6 (Cell-free assay) CDK7 (Cell-free assay)
40 nM40 nM40 nM40 nM300 nM


Solubility (25°C) * In vitro DMSO 88 mg/mL (200.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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