Flavopiridol (Alvocidib)

Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia.
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Product Name Price Stock Qty
Flavopiridol 5mg
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Flavopiridol 10mg
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Flavopiridol 25mg
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Flavopiridol 50mg
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Flavopiridol (Alvocidib) 10mM * 1mL in DMSO
In stock

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Flavopiridol (Alvocidib) has been cited by 3 publications
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Zhiyuan Zhao, .et al. , J Biol Chem, 2017, Sep 15; 292(37): 15489-15500 PMID: 28743741
  • Sami Kukkonen, .et al. , Retrovirology., 2014, 11: 30. PMID: 24742347
  • Biological Activity
    Discription Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia.
    Target Value
    Chemical Information
    Catalog Num A10390
    Formula C21H20ClNO5
    Molecular Weight 401.8
    CAS Number 146426-40-6
    SMILES CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O
    Synonyms HMR-1275, L868275

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 14 mg/mL (34.83 mM)
    Water Insoluble
    Ethanol 7 mg/mL (17.41 mM)
    In vivo 5% DMSO+30% PEG 300+ddH2O 2.3 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.89 mL 124.44 mL 248.88 mL
    0.5 mM 4.98 mL 24.89 mL 49.78 mL
    1 mM 2.49 mL 12.44 mL 24.89 mL
    5 mM 0.5 mL 2.49 mL 4.98 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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