FRAX486
FRAX486 is a small-molecule PAK inhibitor.
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Adooq Products cited in reputable paper
Adooq's FRAX486 has been cited by 2 publications
- Natalia Barraza-Nunez, .et al. , Neurotox Res, 2023, Mar 3 PMID: 36867391
- Yukie Yamahashi, .et al. , Mol Psychiatry, 2022, 03 June
Biological Activity
| Description | FRAX486 is a small-molecule PAK inhibitor. | ||
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| Targets |
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Product Information
| Catalog Num | A13691 |
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| Formula | C25H23Cl2FN6O |
| Molecular Weight | 513.39 |
| CAS Number | 1232030-35-1 |
| SMILES | CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F |
| Synonyms | FRAX 486, FRAX-486 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 21 mg/mL (40.9 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.48 mL | 97.39 mL | 194.78 mL |
| 0.5 mM | 3.9 mL | 19.48 mL | 38.96 mL |
| 1 mM | 1.95 mL | 9.74 mL | 19.48 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.9 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
