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GSK-2193874

TRPV4 blocker

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Catalog No. A14201

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK-2193874 10mg A14201-10

Regular Price: $150.00

Special Price: $120.00

GSK-2193874 25mg A14201-25

Regular Price: $300.00

Special Price: $240.00

GSK-2193874 50mg A14201-50

Regular Price: $500.00

Special Price: $400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits Ca(2+) influx through recombinant TRPV4 channels and native endothelial TRPV4 currents.

GSK-2193874

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Chemical Information

Catalog Num A14201
Actions Blocker
M. Wt 691.62
Formula C37H38BrF3N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1336960-13-4
Synonyms GSK 2193874, GSK2193874
SMILES code C1CCN(CC1)C2CCN(CC2)CC3=C(N=C4C=C(C=CC4=C3C(=O)NC5(CC5)C6=CC=CC=C6)Br)C7=CC(=CC=C7)C(F)(F)F
Chemical Name 3-([1,4-Bipiperidin]-1-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide

Biological Activity

Description
GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits Ca(2+) influx through recombinant TRPV4 channels and native endothelial TRPV4 currents.

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