GSK690693

Catalog No.: A11030
AKT inhibitor
GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).
Grouped product items
Product Name Stock
GSK690693 10mg
GSK690693 25mg
GSK690693 50mg
GSK690693 100mg
GSK690693 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's GSK690693 has been cited by 1 publications
  • Khan MI, .et al. , Prog Neuropsychopharmacol Biol Psychiatry, 2018, Mar 2;82:39-48 PMID: 9223784
  • Biological Activity
    Discription GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).
    Targets
    Target Value
    Product Information
    Catalog Num A11030
    Formula C21H27N7O3
    Molecular Weight 425.5
    CAS Number 937174-76-0
    SMILES CCN1C2=C(C(=NC=C2OC[C@H]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
    Synonyms GSK-690693
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 36 mg/mL (84.61 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40%PEG300+5% tween80+50% H2O 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.5 mL 117.51 mL 235.02 mL
    0.5 mM 4.7 mL 23.5 mL 47 mL
    1 mM 2.35 mL 11.75 mL 23.5 mL
    5 mM 0.47 mL 2.35 mL 4.7 mL
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    This equation is commonly abbreviated as: C1V1 = C2V2

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