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TRPA1 inhibitor

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Catalog No. A13278

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
HC-030031 50mg A13278-50

Regular Price: $120.00

Special Price: $108.00

HC-030031 100mg A13278-100

Regular Price: $180.00

Special Price: $162.00

HC-030031 200mg A13278-200

Regular Price: $250.00

Special Price: $225.00

HC-030031 10mM * 1mL in DMSO A13278-10mM-D

Regular Price: $55.00

Special Price: $49.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 uM, respectively).


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Chemical Information

Catalog Num A13278
Actions Inhibitor
M. Wt 355.4
Formula C18H21N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 349085-38-7
Synonyms HC030031
SMILES code CC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C
Chemical Name 1,?2,?3,?6-?tetrahydro-?1,?3-?dimethyl-?N-?[4-?(1-?methylethyl)phenyl]-?2,?6-?dioxo-?7H-?purine-?7-?acetamide

Biological Activity

HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 uM, respectively).


Solubility (25°C) * In vitro DMSO 32 mg/mL (90.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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