Icotinib

Catalog No.: A13825
EGFR inhibitor
Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
Grouped product items
Product Name Price Stock Qty
Icotinib 5mg
$65.00
In stock
Icotinib 10mg
$90.00
In stock
Icotinib 25mg
$180.00
In stock
Icotinib 50mg
$260.00
In stock
Icotinib 10mM * 1mL in DMSO
$100.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

Other Forms of Icotinib

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Adooq Products cited in reputable paper
Biological Activity
Discription Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
Targets
Target Value
Product Information
Catalog Num A13825
Formula C22H21N3O4
Molecular Weight 391.42
CAS Number 610798-31-7
SMILES C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4
Synonyms BPI-2009H
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 66 mg/mL (168.61 mM)
Water Insoluble
Ethanol 6 mg/mL (15.33 mM)
In vivo 0.5% CMC 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.55 mL 127.74 mL 255.48 mL
0.5 mM 5.11 mL 25.55 mL 51.1 mL
1 mM 2.55 mL 12.77 mL 25.55 mL
5 mM 0.51 mL 2.55 mL 5.11 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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