Icotinib Hydrochloride

Catalog No.: A13718

EGFR inhibitor

Icotinib Hydrochloride

Icotinib Hydrochloride Chemical Structure

CAS NO. 1204313-51-8

Icotinib hydrochloride is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $200.00

Special Price $180.00

10 mg

Regular Price: $340.00

Special Price $306.00

25 mg

Regular Price: $650.00

Special Price $585.00

50 mg

Regular Price: $980.00

Special Price $882.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Icotinib hydrochloride is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.37 mL 116.86 mL 233.71 mL
0.5 mM 4.67 mL 23.37 mL 46.74 mL
1 mM 2.34 mL 11.69 mL 23.37 mL
5 mM 0.47 mL 2.34 mL 4.67 mL

*The above data is based on the productmolecular weight 427.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13718
Actions Inhibitor
M. Wt 427.88
Formula C22H22ClN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1204313-51-8
Synonyms BPI-2009H
SMILES C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl

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