JNK-IN-8

JNK Inhibitor

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Catalog No. A12749

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JNK-IN-8 5mg A12749-5

Regular Price: $110.00

Special Price: $88.00

JNK-IN-8 10mg A12749-10

Regular Price: $180.00

Special Price: $144.00

JNK-IN-8 25mg A12749-25

Regular Price: $300.00

Special Price: $240.00

JNK-IN-8 50mg A12749-50

Regular Price: $540.00

Special Price: $432.00

JNK-IN-8 10mM * 1mL in DMSO A12749-10mM-D

Regular Price: $123.00

Special Price: $98.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively

JNK-IN-8

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Chemical Information

Catalog Num A12749
Actions Inhibitor
M. Wt 507.59
Formula C29H29N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1410880-22-6
Synonyms N/A
SMILES code CC1=C(C=CC(=C1)NC(=O)C2=CC(=CC=C2)NC(=O)/C=C/CN(C)C)NC3=NC=CC(=N3)C4=CN=CC=C4
Chemical Name (E)-3-(4-(dimethylamino)but-2-enamido)-N-(3-methyl-4-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide

Biological Activity

Description
JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL heating (197 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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