Ki16198

LPA Receptor antagonist

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Catalog No. A11966

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Ki16198 5mg A11966-5

Regular Price: $160.00

Special Price: $128.00

Ki16198 10mg A11966-10

Regular Price: $259.00

Special Price: $207.20

Ki16198 25mg A11966-25

Regular Price: $500.00

Special Price: $400.00

Ki16198 50mg A11966-50

Regular Price: $749.00

Special Price: $599.20

Ki16198 10mM * 1mL in DMSO A11966-10mM-D

Regular Price: $215.00

Special Price: $172.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Ki16198 is a potent LPA receptor antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.

Ki16198

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Chemical Information

Catalog Num A11966
Actions Antagonist
M. Wt 488.98
Formula C24H25ClN2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 355025-13-7
Synonyms Ki-16198
SMILES code CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O
Chemical Name Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester

Biological Activity

Description
Ki16198 is a potent LPA receptor antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.
Targets
LPA1 LPA3
0.34 μM(Ki)0.93 μM(Ki)

Solubility

Solubility (25°C) * In vitro DMSO 96 mg/mL (196.32 mM)
Water 96 mg/mL (196.32 mM)
Ethanol 35 mg/mL (71.57 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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