LDN-57444

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UCH-L1 Inhibitor

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Catalog No. A12715

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LDN-57444 10mg A12715-10

Regular Price: $85.00

Special Price: $72.25

LDN-57444 25mg A12715-25

Regular Price: $180.00

Special Price: $153.00

LDN-57444 50mg A12715-50

Regular Price: $300.00

Special Price: $255.00

LDN-57444 100mg A12715-100

Regular Price: $500.00

Special Price: $425.00

LDN-57444 10mM * 1mL in DMSO A12715-10mM-D

Regular Price: $93.00

Special Price: $79.05

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1.

LDN-57444

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Chemical Information

Catalog Num A12715
Actions Inhibitor
M. Wt 397.64
Formula C17H11Cl3N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 668467-91-2
Synonyms C30, LDN 57444, LDN57444
SMILES code CC(=O)O/N=C/1\C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl
Chemical Name 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)

Biological Activity

Description
LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1.
Targets
UCH-L1 UCH-L1 UCH-L3
0.4 μM(Ki)0.88 μM25 μM

Solubility

Solubility (25°C)* In vitro DMSO 11 mg/mL (27.66 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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