p38 MAPK inhibitor

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Catalog No. A10545

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY2228820 5mg A10545-5

Regular Price: $90.00

Special Price: $81.00

LY2228820 10mg A10545-10

Regular Price: $160.00

Special Price: $144.00

LY2228820 50mg A10545-50

Regular Price: $580.00

Special Price: $522.00

LY2228820 100mg A10545-100

Regular Price: $950.00

Special Price: $855.00

LY2228820 10mM * 1mL in DMSO A10545-10mM-D

Regular Price: $120.00

Special Price: $108.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity.


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Chemical Information

Catalog Num A10545
Actions Inhibitor
M. Wt 612.7
Formula C24H29FN6.2CH4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 862507-23-1
Synonyms LY-2228820
SMILES code CC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O
Chemical Name 5-[2-(1,1-Dimethylethyl-d9)-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine Dimethanesulfonate

Biological Activity

LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity.
p38α (Cell-free assay)
7 nM


Solubility (25°C) * In vitro DMSO 35 mg/mL (57.12 mM)
Water 123 mg/mL (200.73 mM)
Ethanol 3 mg/mL (4.89 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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