Mavatrep

TRPV1 antagonist

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Catalog No. A15778

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Mavatrep 2mg A15778-2
$180.00
Mavatrep 5mg A15778-5
$350.00
Mavatrep 10mg A15778-10
$500.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6.

Mavatrep

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Chemical Information

Catalog Num A15778
Actions Antagonist
M. Wt 422.44
Formula C25H21F3N2O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 956274-94-5
Synonyms JNJ-39439335
SMILES code CC(C)(C1=CC=CC=C1C2=CC3=C(C=C2)N=C(N3)C=CC4=CC=C(C=C4)C(F)(F)F)O
Chemical Name (E)-2-(2-(2-(4-(trifluoromethyl)styryl)-1H-benzo[d]imidazol-6-yl)phenyl)propan-2-ol

Biological Activity

Description
Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6.

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