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DRP1 inhibitor

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Catalog No. A14316

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Mdivi-1 25mg A14316-25

Regular Price: $90.00

Special Price: $81.00

Mdivi-1 50mg A14316-50

Regular Price: $160.00

Special Price: $144.00

Mdivi-1 100mg A14316-100

Regular Price: $280.00

Special Price: $252.00

Mdivi-1 10mM * 1mL in DMSO A14316-10mM-D

Regular Price: $80.00

Special Price: $72.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 uM.


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Chemical Information

Catalog Num A14316
Actions Inhibitor
M. Wt 353.22
Formula C15H10Cl2N2O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 338967-87-6
Synonyms Mdivi 1, Mdivi1
SMILES code COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl
Chemical Name 4(1H)-Quinazolinone, 3-(2,4-dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-

Biological Activity

Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 uM.
1 μM-10 μM


Solubility (25°C)* In vitro DMSO 70 mg/mL (198.17 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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