MLN2238

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Proteasome Inhibitor

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Catalog No. A10600

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MLN2238 5mg A10600-5

Regular Price: $90.00

Special Price: $76.50

MLN2238 10mg A10600-10

Regular Price: $120.00

Special Price: $102.00

MLN2238 50mg A10600-50

Regular Price: $350.00

Special Price: $297.50

MLN2238 100mg A10600-100

Regular Price: $600.00

Special Price: $510.00

MLN2238 10mM * 1mL in DMSO A10600-10mM-D

Regular Price: $90.00

Special Price: $76.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MLN2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.

MLN2238

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Chemical Information

Catalog Num A10600
Actions Inhibitor
M. Wt 361.0
Formula C14H19BCl2N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1072833-77-2
Synonyms MLN 2238, MLN-2238
SMILES code B([[email protected]](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O
Chemical Name (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

Biological Activity

Description
MLN2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.
Targets
20S proteasome (Cell-free assay) 20S proteasome (Cell-free assay)
0.93 nM(Ki)3.4 nM

Solubility

Solubility (25°C) * In vitro DMSO 72 mg/mL (199.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol 9 mg/mL (24.92 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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