MLN9708

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Proteasome Inhibitor

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Catalog No. A10602

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MLN9708 5mg A10602-5
$60.00
MLN9708 10mg A10602-10
$80.00
MLN9708 50mg A10602-50
$150.00
MLN9708 100mg A10602-100
$250.00
MLN9708 10mM * 1mL in DMSO A10602-10mM-D
$60.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.

MLN9708

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Chemical Information

Catalog Num A10602
Actions Inhibitor
M. Wt 517.1
Formula C20H23BCl2N2O9
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1201902-80-8
Synonyms MLN-9708
SMILES code B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[[email protected]](CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
Chemical Name 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid

Biological Activity

Description
MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.
Targets
20S proteasome (Cell-free assay) 20S proteasome (Cell-free assay)
0.93 nM(Ki)3.4 nM

Solubility

Solubility (25°C) * In vitro DMSO 100 mg/mL (193.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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