NF 279 P2X1 antagonist

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Catalog No. A11972

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NF 279 10mg A11972-10
$120.00
NF 279 25mg A11972-25
$250.00
NF 279 50mg A11972-50
$420.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 ??M in smooth muscle).

NF 279

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Chemical Information

Catalog Num A11972
Actions Antagonist
M. Wt 1401.1
Formula C49H30N6Na6O23S6
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 202983-32-2
Synonyms NF279, NF-279
SMILES code C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Chemical Name 8,8'-[Carbonylbis(imino-4,1-phenylen?ecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3?,5-naphthalenetrisulfonic acid hexasodium salt

Biological Activity

Description
NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 ??M in smooth muscle).

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