NKP608

NK1 receptor antagonist

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Catalog No. A15187

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NKP608 5mg A15187-5
$200.00
NKP608 10mg A15187-10
$300.00
NKP608 50mg A15187-50
$800.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.

NKP608

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Chemical Information

Catalog Num A15187
Actions Antagonist
M. Wt 619.98
Formula C31H24ClF6N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 177707-12-9
Synonyms NK 608, NK-608
SMILES code C1CN(C(CC1NC(=O)C2=CC=NC3=CC=CC=C23)CC4=CC=C(C=C4)Cl)C(=O)C5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F
Chemical Name N-[(2R,4S)-1-[3,5-bis(trifluoromethyl)benzoyl]-2-[(4-chlorophenyl)methyl]piperidin-4-yl]quinoline-4-carboxamide

Biological Activity

Description
NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.

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