NSC 405020
NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).
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Adooq Products cited in reputable paper
Adooq's NSC 405020 has been cited by 1 publications
- Kittaka M, .et al. , J Bone Miner Res, 2018, Jan;33(1):167-181 PMID: 28914985
Biological Activity
| Description | NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L). | ||
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Product Information
| Catalog Num | A13072 |
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| Formula | C12H15Cl2NO |
| Molecular Weight | 260.16 |
| CAS Number | CAS: 7497-07-6 |
| SMILES | CCCC(C)NC(=O)C1=CC(=C(C=C1)Cl)Cl |
| Synonyms | NSC405020, NSC-405020 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 48 mg/mL (184.5 mM) | |
| Water | Insoluble | ||
| Ethanol | 48 mg/mL (184.5 mM) | ||
| In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.44 mL | 192.19 mL | 384.38 mL |
| 0.5 mM | 7.69 mL | 38.44 mL | 76.88 mL |
| 1 mM | 3.84 mL | 19.22 mL | 38.44 mL |
| 5 mM | 0.77 mL | 3.84 mL | 7.69 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
