PD 169316
PD 169316 (PD169316) is a selective inhibitor of p38 MAPK.1 that inhibits p38 MAPK with an IC50 of 89 nM.
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Adooq Products cited in reputable paper
Adooq's PD 169316 has been cited by 1 publications
- Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
Biological Activity
| Description | PD 169316 (PD169316) is a selective inhibitor of p38 MAPK.1 that inhibits p38 MAPK with an IC50 of 89 nM. |
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Product Information
| Catalog Num | A11221 |
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| Formula | C20H13FN4O2 |
| Molecular Weight | 360.3 |
| CAS Number | 152121-53-4 |
| SMILES | C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)[N+](=O)[O-] |
| Synonyms | PD-169316, PD169316 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 12 mg/mL (33.3 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.75 mL | 138.77 mL | 277.55 mL |
| 0.5 mM | 5.55 mL | 27.75 mL | 55.51 mL |
| 1 mM | 2.78 mL | 13.88 mL | 27.75 mL |
| 5 mM | 0.56 mL | 2.78 mL | 5.55 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
