PF-3845 ON SALE FAAH Inhibitor

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Catalog No. A11183

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PF-3845 10mg A11183-10

Regular Price: $70.00

Special Price: $59.50

PF-3845 50mg A11183-50

Regular Price: $300.00

Special Price: $255.00

PF-3845 100mg A11183-100

Regular Price: $500.00

Special Price: $425.00

PF-3845 10mM * 1mL in DMSO A11183-10mM-D

Regular Price: $91.00

Special Price: $77.35

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It reduces inflammatory pain via a cannabinoid receptor-dependent mechanism.

PF-3845

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Chemical Information

Catalog Num A11183
Actions Inhibitor
M. Wt 456.46
Formula C24H23F3N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1196109-52-0
Synonyms PF3845
SMILES code C1CN(CCC1CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=CN=CC=C4
Chemical Name N-3-Pyridinyl-4-[[3-[[5-(trifluorom ethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidine carboxamide

Biological Activity

Description

PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It reduces inflammatory pain via a cannabinoid receptor-dependent mechanism.

Targets
FAAH
230 nM(Ki)

Solubility

Solubility (25°C) * In vitro DMSO 91 mg/mL (199.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol 91 mg/mL (199.36 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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