PF-3845

Catalog No.: A11183
FAAH Inhibitor

PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It reduces inflammatory pain via a cannabinoid receptor-dependent mechanism.

Grouped product items
Product Name Price Stock Qty
PF-3845 10mg
$70.00
In stock
PF-3845 50mg
$300.00
In stock
PF-3845 100mg
$500.00
In stock
PF-3845 10mM * 1mL in DMSO
$91.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription

PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It reduces inflammatory pain via a cannabinoid receptor-dependent mechanism.

Targets
Target Value
Product Information
Catalog Num A11183
Formula C24H23F3N4O2
Molecular Weight 456.46
CAS Number 1196109-52-0
SMILES C1CN(CCC1CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=CN=CC=C4
Synonyms PF3845
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 87 mg/mL (190.6 mM)
Water Insoluble
Ethanol 87 mg/mL (190.6 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.91 mL 109.54 mL 219.08 mL
0.5 mM 4.38 mL 21.91 mL 43.82 mL
1 mM 2.19 mL 10.95 mL 21.91 mL
5 mM 0.44 mL 2.19 mL 4.38 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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