PH-797804

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p38 MAPK inhibitor

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Catalog No. A11078

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PH-797804 5mg A11078-5
$110.00
PH-797804 10mg A11078-10
$200.00
PH-797804 50mg A11078-50
$620.00
PH-797804 100mg A11078-100
$1,050.00
PH-797804 10mM * 1mL in DMSO A11078-10mM-D
$164.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.

PH-797804

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Chemical Information

Catalog Num A11078
Actions Inhibitor
M. Wt 477.2
Formula C22H19BrF2N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 586379-66-0
Synonyms PH797804
SMILES code CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C
Chemical Name (aS)-3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamde

Biological Activity

Description
PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.
Targets
p38α (Cell-free assay) p38β (Cell-free assay)
26 nM102 nM

Solubility

Solubility (25°C) * In vitro DMSO 96 mg/mL (201.13 mM)
Water <1 mg/mL (<1 mM)
Ethanol 7 mg/mL (14.66 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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