PH-797804
PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.
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Adooq Products cited in reputable paper
Adooq's PH-797804 has been cited by 1 publications
- Yuho Ito, .et al. , Biosci Biotechnol Biochem, 2015, 79(11):1794-801 PMID: 26057585
Biological Activity
| Description | PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A11078 |
|---|---|
| Formula | C22H19BrF2N2O3 |
| Molecular Weight | 477.2 |
| CAS Number | 586379-66-0 |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C |
| Synonyms | PH797804 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 84 mg/mL (175.99 mM) | |
| Water | Insoluble | ||
| Ethanol | 6 mg/mL (12.57 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.96 mL | 104.78 mL | 209.56 mL |
| 0.5 mM | 4.19 mL | 20.96 mL | 41.91 mL |
| 1 mM | 2.1 mL | 10.48 mL | 20.96 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.19 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
