PIK-90

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PI3K Inhibitor

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Catalog No. A10730

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PIK-90 5mg A10730-5

Regular Price: $40.00

Special Price: $32.00

PIK-90 10mg A10730-10

Regular Price: $60.00

Special Price: $48.00

PIK-90 50mg A10730-50

Regular Price: $200.00

Special Price: $160.00

PIK-90 100mg A10730-100

Regular Price: $350.00

Special Price: $280.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.

PIK-90

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Chemical Information

Catalog Num A10730
Actions Inhibitor
M. Wt 351.4
Formula C18H17N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 677338-12-4
Synonyms PIK90
SMILES code COC1=C(C2=C(C=C1)C3=NCCN3C(=N2)NC(=O)C4=CN=CC=C4)OC
Chemical Name N-(7,8-Dimethoxy-2,3-dihydro-imidazo[1,2-c]quinazolin-5-yl)-nicotinamide

Biological Activity

Description
PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.
Targets
PI3Kα PI3Kγ PI3Kδ PI3Kβ
11 nM18 nM58 nM350 nM

Solubility

Solubility (25°C) * In vitro DMSO 0.28 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80, pH 4 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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