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Q-VD-OPh hydrate

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Caspase inhibitor

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Catalog No. A14915

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Q-VD-OPh hydrate 5mg A14915-5

Regular Price: $90.00

Special Price: $72.00

Q-VD-OPh hydrate 10mg A14915-10

Regular Price: $150.00

Special Price: $120.00

Q-VD-OPh hydrate 25mg A14915-25

Regular Price: $240.00

Special Price: $192.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).

Q-VD-OPh hydrate

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Chemical Information

Catalog Num A14915
Actions Inhibitor
M. Wt 513.49
Formula C26H25F2N3O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1135695-98-5
Synonyms N/A
SMILES code CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2
Chemical Name (3S)-5-(2,6-Difluorophenoxy)-3-[[(2S)-3-methyl-1-oxo-2-[(2-quinolinylcarbonyl)amino]butyl]amino]-4-oxo-pentanoic acid

Biological Activity

Description
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
Targets
Caspase-1 Caspase-3 Caspase-8 Caspase-9
25 nM-400 nM25 nM-400 nM25 nM-400 nM25 nM-400 nM

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